Index: Type III PKS

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(Last modification: 16. November 2010)

Index of Type III Polyketide Synthase Pages

0.0.0.0.0..English Start Site
0.1.0.1.0........Resveratrol: Basic Aspects and Biosynthesis
0.1.0.1.1.0.......New: Human Sirtuins: Structure, Enzyme Activities, Functions
0.1.0.1.1.1.........New: Sirtuin Activators (e.g. Resveratrol)
0.1.0.1.1.2.........New: Sirtuin Inhibitors (Cancer Suppression by Inhibitors?)
0.1.0.1.1.3.........New: Sirtuins: Selected References
0.1.0.1.1.4.........New: Human Sirtuins: Sequences
0.1.0.1.2...........Resveratrol: Some References of Interest and Links to some Internet Pages
0.1.0.1.3........Resveratrol in Transgenic Plants and Other Organisms
0.1.0.1.4...........Resveratrol in Transgenic Plants: References
1.0.0.0.0....Projects Overview
1.1.0.0.0......Type III PKS: CHS-Related Polyketide Synthases
1.1.0.0.1........Book 2006: Polyketides: Biosynthesis, Biological Activity, and Genetic Engineering
1.1.0.0.2........New Book 2010: Comprehensive Natural Products II, Chemistry and Biology
1.1.0.1.0........Multiplicity of Products Synthesized via Type III PKS: Plants, Fungi, Bacteria
1.1.0.1.1........Overview of Enzyme Reactions of Plant Type III PKS
1.1.0.1.2..........PDF File: Relationship Tree of Selected Plant Type III PKS
1.1.0.1.3..........Links to Sequences of the Relationship Tree
1.1.0.1.3.1..........Accession numbers: 1 and 2 Condensation Reactions
1.1.0.1.3.2..........Accession numbers: 3 Condensation Reactions CHS-type
1.1.0.1.3.3..........Accession numbers: 3 Condensation Reactions STS-type
1.1.0.1.3.4..........Accession numbers: 4 and more Condensation Reactions
1.1.0.1.3.5..........Accession numbers: Other Type III PKS
1.1.0.1.3.6..........Accession numbers: Type III PKS from Rheum palmatum
1.1.0.1.3.7..........Accession numbers: Type III PKS from Aloe arborescens
1.1.0.1.4..........Prosite Pattern of Active Site
1.1.01.0.0........Plants: One condensation
1.1.01.1.0..........Benzalacetone Synthase
1.1.01.1.1.............Benzalacetone Synthase in Raspberries (Rubus idaeus)
1.1.01.1.2.............Benzalacetone Synthase in Rheum palmatum (13.05.2010)
1.1.01.3.0..........C-Methylated Flavonoids in Pinus strobus
1.1.01.3.1.............Biosynthesis of C-Methylated Flavonoids: Results, Proposal, and Model
1.1.01.3.2.............Comparison of Pinus strobus CHS1 and CHS2
1.1.01.4.0..........Phenylphenalenones and Model of Biosynthesis
1.1.01.4.1.............Phenylphenalenones: An Introduction
1.1.01.4.2.............Phenylphenalenones in Wachendorfia thyrsifolia
1.1.01.4.3.............WtPKS1, a type III PKS from Wachendorfia thyrsifolia
1.1.01.4.5.............In vitro Products of recombinant WtPKS1
1.1.01.4.6.............Discussion: WtPKS1 from Wachendorfia thyrsifolia
1.1.01.4.7.............WtPKS1: One Enzyme of a Two-Component System?
1.1.01.5.0..........Curcumin Synthesis in Curcuma longa: Two Cooperating Enzymes
1.1.01.9.1..........Proposal: Quinolines
1.1.01.9.2..........Proposal: 4-Hydroxycoumarins
1.1.01.9.3..........Proposal: Psilotonin in Psilotum nudum
1.1.01.9.4..........Proposal: Benzylacetone Synthase
1.1.02.0.0........Plants: Two Condensations
1.1.02.1.0...........Pyrone Synthase (Gerbera hybrida)
1.1.02.1.1.............Pyrone Synthase: Enzyme Reaction
1.1.02.1.2.............Pyrone Synthase: Keys to the Active Site Pockets
1.1.02.1.3.............Conversion of CHS into Pyrone Synthase
1.1.02.1.4.............Active Site Size Comparison of CHS and 2PS
1.1.02.1.5.............Cover Picture from Chemistry & Biology (2000)
1.1.02.4.1...........Proposal: Styrylpyrone Synthase (SPS) in Equisetum arvense
1.1.03.0.0........Plants: Three Condensations
1.1.03.1.0...........Comparison of chalcone (CHS) and stilbene synthase (STS) Reactions
1.1.03.1.1.............Brief Overview: Biology of Chalcone and Stilbene Synthase Products
1.1.03.1.1.1.............Picture: Flavonoid Pills
1.1.03.1.6.............Comment on Resveratrol in the Freiburger Uni Magazin (December 2004)
1.1.03.2.0..........Chalcone Synthase (CHS)
1.1.03.2.1.............CHS Reaction Mechanisms
1.1.03.2.4............CHS-type Ring-Folding: Other Enzymes
1.1.03.2.4.1.............Acridone Synthase (ACS)
1.1.03.2.4.2.............Benzophenone Synthase (BPS)
1.1.03.2.4.3.............Valerophenone Synthase (VPS)
1.1.03.2.4.4.............DIF-1 in Dictyostelium discoideum
1.1.03.2.4.8.............Proposal: Hyperforin Biosynthesis
1.1.03.3.0..........Stilbene Synthase (STS)
1.1.03.3.0.1...........STS: Reaction Mechanisms
1.1.03.3.0.2...........STS: 3D Structure
1.1.03.3.0.3...........STS: "Aldol Switch"
1.1.03.3.0.4...........STS: The Hydrogen-Bond Network
1.1.03.3.0.5...........STS: Scenario of STS-type Cyclization
1.1.03.3.0.6...........New in April 2010: STS: Generalization of the Aldol Switch? (13.05.2010)
1.1.03.3.1............STS from Pinus strobus: Effects of a Single Amino Acid Difference
1.1.03.3.2............STS-type Ring-Folding: Other Enzymes
1.1.03.3.2.1............Biphenyl Synthase (BPS) from Sorbus aucuparia
1.1.03.3.2.2............Alkylresorcinol Synthase in Sorghum bicolor
1.1.03.3.2.3............4-Methyl-5-pentylbenzene-1,3-diol in Dictyostelium discoideum
1.1.03.3.2.4............New: Proposal for Bis-5-Alkylresorcinol Biosynthesis
1.1.03.3.2.8.1..........Proposal: Olivetolic Acid and Bibenzyls in Cannabis sativa
1.1.03.4.0..........Stilbenecarboxylate Synthases (STCS)
1.1.03.4.1...............Hydrangea macrophylla
1.1.03.4.1.1...............Hydrangea Type III PKS
1.1.03.4.1.2...............Sequences: Hydrangea macrophylla
1.1.03.4.2...............Hydrangea macrophylla var. thunbergii
1.1.03.4.3...............Marchantia polymorpha
1.1.03.4.3.1...............Marchantia polymorpha STCS2 3D-Structure
1.1.03.4.3.2...............Sequences: Marchantia polymorpha
1.1.03.4.4...............Proposal: Anacardic Acid and Urushiol (13.05.2010)
1.1.03.4.5...............STCS: Just a "Degenerate" STS or CHS ?
1.1.04.0.0....... Plants: More than Three Condensations
1.1.04.1.0...............Four Condensations: Chromone Synthase (PCS)
1.1.04.1.1...............Four Condensations: Proposal for 4-Hydroxy-5-Methylcoumarin
1.1.04.1.1...............Vier Kondensationen: Vorschlag für 4-Hydroxy-5-Methylcoumarin
1.1.04.2.0...............Five Condensations: Plumbagin
1.1.04.3.0...............Six Condensations: Aloesone
1.1.04.4.1...............Seven Condensations: Anthrone in Aloe arborescens
1.1.04.4.2...............Seven Condensations: Hypericin in Hypericum perforatum
1.1.04.5.0...............Functional Interconversion between Four and Seven Condensations
1.1.05.0.0........'Orphan PKS': Proteins in Search of a Physiological Role
1.1.05.1.0................'Orphan PKS': Ipomoea (10.05.2010)
1.1.05.2.0................'Orphan PKS': Huperzia serrata
1.1.05.3.0................'Orphan PKS': Curcuminoid synthase from Rice (Oryza sativa) (10.05.2010)
1.1.05.3.1...................Relationship Tree: Type III PKS in Oryza sativa (PDF-file)
1.1.05.4.0................'Orphan PKS': Alkylpyrone/Alkylresorcinol Synthase from Physcomitrella patens
1.1.05.5.0................'Orphan PKS': Alkylpyrone Synthases from Arabidopsis thaliana
1.1.08.0.0........Byproducts, Promiscuity, Functional Identification
1.1.09.0.0........Polyketide reductases (PKR)
1.1.09.1.0........... PKR in the Biosynthesis of 6'-Deoxychalcone
1.1.09.2.0............PKR in the Biosynthesis of Stilbenecarboxylic Acids
1.1.21.0.0........Fungi
1.1.21.1.0............PKS Reactions in Fungi: Type I, but Hardly Type III PKS ?
1.1.21.2.0............Relationship Tree of Type III PKS from Fungi and Plants
1.1.21.3.0............Neurospora crassa: Oxoalkylresorcylic Acid Synthase (ORAS)
1.1.21.4.0............New in June, update August 2010: Pyrone Synthases from Aspergillus oryzae
1.1.21.5.0............Proposal: Palitantin and Frequentin Biosynthesis
1.1.21.6.0............Accession numbers: Fungal Type III PKS
1.1.31.0.0........Bacteria
1.1.31.1.0............Tree of Type III PKS in Bacteria (PDF-file)
1.1.31.1.1............Accession numbers: Bacterial Type III PKS
1.1.31.2.1............Complex Ring-Folding: 1,3,6,8-Tetrahydroxynaphthalene
1.1.31.3.1............CHS-Type: 2,4-Diacetylphloroglucinol in Pseudomonads
1.1.31.4.1............STS-Type: (S)-3,5-Dihydroxyphenylglycine in Streptomycetes
1.1.31.4.1.1..............Balhimycin Structure
1.1.31.4.2............STS-Type: in Alkylresorcinol Biosynthesis in Streptomyces
1.1.31.5.1............STS and Pyrone Type Ring-Folding: Cyst Formation in Azotobacer vinelandii
1.1.31.6.1............Pyrone: Germicidin in Streptomyces coelicolor
1.1.31.7.1............'Orphans': Pyrone Synthases from Mycobacterium tuberculosis and Bacillus subtilis
1.1.31.8.1............New in August 2010: Unusual: Stilbene Synthesis in the bacterium Photorhabdus luminescens
4.00.0.0.0...Plant Photos and some Comments
4.02.0.0.0........Peanut (Arachis hypogaea)
4.03.0.0.0........Scots Pine (Pinus sylvestris)
4.04.0.0.0........Eastern White Pine (Pinus strobus)
4.05.0.0.0........Kangaroo paws
4.06.0.0.0........Ginger (Zingiber officinale)
4.07.0.0.0........Curry (Curcuma longa)
4.08.0.0.0........Psilotum nudum
4.09.0.0.0........Gerbera hybrida
4.10.0.0.0........Raspberry (Rubus idaeus)
4.11.0.0.0........Rheum palmatum
4.12.0.0.0........Ipomoea: Pictures and Comments (10.05.2010)
4.13.0.0.0........Anacardiaceae: Cashews, Poison Ivy, Mango...
5.0.0.0.0..Selected Plants and Secondary Products
5.1.0.0.0....Polygonum cuspidatum
5.1.0.1.0...........Polygonum cuspidatum tree (PDF file)
5.1.0.2.0...........Polygonum cuspidatum: References
5.1.0.3.0...........Accession numbers: Type III PKS from Polygonum cuspidatum
5.2.0.0.0....Vitis vinifera
5.2.0.1.0.........Vitis vinifera: Stilbenes described 1995-2008
5.2.0.2.0.........Vitis vinifera: References
5.3.0.0.0....New in October 2010: Peanut (Arachis hypogaea)
5.3.0.1.0.........Arachis hypogaea References
5.4.0.0.0....Hemp (Cannabis sativa): Cannabinoids
5.4.0.1.0........ Cannabis sativa References (Part 1)
5.4.0.1.1........ Cannabis sativa References (Part 2)
5.5.0.0.0....Sorghum bicolor (Sorgoleone Biosynthesis)
5.5.2.0.0.......Alkylresorcinol Synthase in Sorghum bicolor
5.5.2.0.1...........Tissue-Specific Expression of Type III PKS Sequences from Sorghum bicolor
5.5.2.0.2...........Enzyme Activities: Alkylresorcinol Synthases from Sorghum bicolor
5.5.2.0.3...........Modelling: Alkylresorcinol Synthase from Sorghum bicolor
5.5.2.0.4...........ARS Genes and Enzymes from Oryza sativa
5.5.2.0.5...........Sequence Alignment and Identification of Functional Amino Acids: ARS from S. bicolor and O. sativa
5.5.2.0.6...........RNAi Mediated Repression of ARS1 and ARS2 in Sorghum bicolor
5.5.2.0.7...........Alkylresorcinol Synthases: Sequences from Sorghum bicolor and Oryza sativa

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